Unexpected late graft failure 9 months after HLA-identical bone marrow transplant (BMT) for chronic myeloid leukemia (CML): treatment with a second BMT.

نویسندگان

  • J J Gil-Fernández
  • R Arranz
  • R Cámara
  • A Alegre
  • A Figuera
  • J M Fernández-Rañada
چکیده

We describe a patient with CML in 1st chronic phase (CP) who experienced a graft failure 9 months after an HLA genotypically identical sibling BMT. Drug toxicity, viral infections, chronic graft-versus-host-disease (GVHD) or leukemic relapse were excluded. Chimerism study showed 85% of donor marrow cells. She underwent a second BMT, reengrafted but died of grade IV acute GVHD.

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عنوان ژورنال:
  • Haematologica

دوره 83 3  شماره 

صفحات  -

تاریخ انتشار 1998